Registration Dossier
Registration Dossier
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EC number: 204-823-8 | CAS number: 127-09-3
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 2 720 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Dose descriptor:
- LC50
- Value:
- 5 810 mg/m³ air
Acute toxicity: via dermal route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 28 269.15 mg/kg bw
Additional information
Based on the experimental results obtained (reported under the endpoint record 07.02.01_05 KAc) with the analogue Potassium Acetate (LD 50 for male rats = 3.25 (2.48-4.26) g/kg) and the molecular weights, the read-across approach is applied and the LD50 for substance Sodium Acetate is calculated to be 2.72 (2.07-3.56) g/kg bw.
Based on the experimental results (reported under the endpoint record 07.02.02_02 CaAc) obtained with the analogue Calcium Acetate (LC 50 for female rats > 5.6 mg/L air) and the molecular weights, the read-across approach is applied and the LC50 for substance Sodium Acetate is calculated to be higher than 5.81 mg/L air under test conditions.
Based on the experimental results (reported under the endpoint record 07.02.03_02 Fumaric Acid) obtained with the analogue Fumaric Acid (LD 50 for New Zealand rabbits > 20000 mg/kg bw) and the molecular weights, the read-across approach is applied and the LD 50 for substance Sodium Acetate is calculated to be greater than 28269.15 mg/kg bw under test conditions.
Justification for classification or non-classification
Acute toxicity:
Oral: LC50>2000mg/kg bw: non- classification
Dermal: LC50>2000mg/kg bw: non- classification
Inhalation: LC50>5 mg/L: non-classification
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