Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 277-551-0 | CAS number: 73609-36-6
Endpoint summary
Administrative data
Description of key information
[2-(Perfluorohexyl)ethyl]dichloro(methyl)silane hydrolyses rapidly in contact with water and moist air, releasing two moles of hydrogen chloride (HCl) for each mole of parent material. Severe skin, eye and respiratory damage would be expected due to release of HCl.
Key value for chemical safety assessment
Skin irritation / corrosion
Link to relevant study records
- Endpoint:
- skin irritation: in vitro / ex vivo
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is a strong acid (pH ≤ 2.0) or base (pH ≥ 11.5) and the available information indicates that it should be classified as skin corrosion (Category 1, 1A, 1B or 1C)
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
[2-(Perfluorohexyl)ethyl]dichloro(methyl)silane is a chlorosilane, generating hydrogen chloride in the presence of moisture; it is expected to be corrosive. Therefore, in accordance with Column 2 of REACH Annex VIII, the in vitro skin and eye irritation studies (required in Section 8.1.1 and 8.2.1) do not need to be conducted as the available information indicates that the substance meets the criteria for classification as corrosive to skin.
Justification for classification or non-classification
[2-(perfluorohexyl)ethyl]dichloro(methyl)silane is classified 'Skin Corr. 1A' and 'Eye Dam. 1', with hazard statement H314 'Causes severe skin burns and eye damage' according to Regulation (EC) No 1272/2008.
Consistent with other chlorosilanes, the additional classification EUH071 'Corrosive to respiratory tract' is also proposed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
