Phenetole

Endpoint summary

Additional information

Stability

Phototransformation in air

The atmospheric oxidation half-life of Phenetole was estimated using the level III multimedia model.It was estimated that the substance is not persistent in air medium as the half life period of Phenetole in air is only 0.58 day.This indicates that Phenetole is rapidly phototransformed in air.

OVERALL OH Rate Constant =0.000000000028cm3/molecule-sec.

Hydrolysis

The Hydrolysis rate constant of Phenetole is estimated to be 0.0000000000276774 cm3/molecule-sec.at half life of 4.637 Hrs.The estimated half life of the substance indicates that the substance is moderately hydrolysable.

Phototransformation in water

No experimental data available. As this study is not a standard information requirement in REACH and there is no indication from the CSA on the need to investigate further the fate and behaviour of the substance (Annex X requirement), no further testing is considered necessary.

Phototransformation in soil

No experimental data available. As this study is not a standard information requirement in REACH and there is no indication from the CSA on the need to investigate further the fate and behaviour of the substance (Annex X requirement), no further testing is considered necessary.

Biodegradation:

Biodegradation in water

The half life period of Phenetole in water is 15 days and based on this value it can be concluded that the chemical is not persistent in water medium since the half life is less than the threshold of 120 days (to qualify the chemical as persistent). Also the diffusion percentage of Phenetole in water medium is 26%. This coupled with the dilution of water shall result in ready biodegradabililty of the chemical.

Biodegradation in water and sediment

Based on the Level III Fugacity Model, the half life period of thePhenetolewas estimated. The half period ofPhenetolein water is 15 days (360 hrs) therefore it is considered that the substance will qualify as not persistent as the half life does not exceed the criteria of 120 days. So, it can be confirmed that the substance is readily biodegradable in water medium where as in sediment the half life is 140 days (3360 hrs).

Based on this value, it can be inferred that the substance is persistent in sediment medium and is not readily biodegradable probably due to the anaerobic conditions existing in most sediments. However, it can be observed that Phenetoledoes not diffuse in the sediment medium since it's percentage in the sediment medium is reported to be 0% and hence persistence in the sediment compartment is not likely to be critical.

Media	Half-Life  (days)	Percent in Each Medium
Water	15	26%
Sediment	140	0%

Biodegradation in soil

The PBT Profiler & EPI Suite has estimated thatPhenetoleis expected to be found predominantly in soil and its persistence estimate is based on its transformation in this medium.Its half-life in soil, 30 days (720 hrs). does not exceeds the criteria of 120 days . Therefore,Phenetoleis estimated not to be persistent in the soil environment.

PBT profiler estimate

Media	Half-Life  (days)	Percent in Medium
Soil	30	71%

 EPI Suite:-

	Mass Amount (percent)	Half-Life (hr)	Emissions (kg/hr)
Soil	73.4	720	1000

 

	Fugacity (atm)	Reaction (kg/hr)	Advection (kg/hr)	Reaction (percent)	Advection (percent)
Soil	3.17e-008	668	0	22.3	0

 

Bioaccumulation:

No. of studies reviewed for Bioaccumulation from reliable sources having Klimish rating 2 and 4

The summary of the results are presented below

 

Sr.no.	Endpoint name	value	Remark
1	BCF	21	Estimated
2	BCF	21.04	Estimated
3	BCF	48	Estimated
4	BCF	35.481	Estimated

 

Based on the above the endpoint varies between 21 to 35.481.  therefore it can be concluded that the substance Phenetole is not expected to bioaccumulation in the food chain because it does not exceed the BCF criteria of 2000.

Adsorption/desorption:

No. of studies reviewed for Adsorption / desorption endpoint from reliable sources having Klimish rating 2 and 4

The summary if the results are presented below

 

Sr.no.	Endpoint name	value	Mobility
1	KoC	170.2	Low tendency of sorption to soil
2	KoC	550	Moderately mobile in soil.
3	KoC	217.27	Moderately mobile in soil.

 

Based on the above the endpoint varies between 170.2 to 550 therefore it can be concluded that the substance Phenetolis expected to have low to moderately mobility in soil.

Henry's Law constant:

Henry's Law states that at a constant temperature,the amount of a given gas that dissolves in a given type and volume of liquid is directly proportional to the partial pressure of that gas in equilibrium with that liquid. Henry’s law constant ofPhenetolewas estimated to be 42.9 Pa m³/mol at 25 deg.C