Registration Dossier
Registration Dossier
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EC number: 205-531-3 | CAS number: 142-28-9
Long-term toxicity to fish
Administrative data
- Endpoint:
- fish early-life stage toxicity
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1982
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- cited from US EPA collection of data (Charles T. Walbridge, James T. Fiandt, Gary L. Phipps, and Gary W. Holcombe, Acute Toxicity of Ten Chlorinated Aliphatic Hydrocarbons to the Fathead Minnow (Pimephales promelas) Arch. Environ. Contam. Toxicol. 12, 661-666 (1983))
Data source
Reference
- Reference Type:
- publication
- Title:
- fathead minnow (Pimephales promelas) early life stage toxicity test method evaluation and exposure to four organic chemicals.
- Author:
- Benoit, D. A., E A. Puglisi, and D. L. Olson
- Year:
- 1 982
- Bibliographic source:
- J. Environ. Pollut. 28, 189 (1982).
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 210 (Fish, Early-Life Stage Toxicity Test)
- Version / remarks:
- early life stage toxicity test method not specified
- Deviations:
- not specified
- GLP compliance:
- not specified
- Remarks:
- Quality maintained by educational and professional experience of experimentators/authors
Test material
- Reference substance name:
- 1,3-dichloropropane
- EC Number:
- 205-531-3
- EC Name:
- 1,3-dichloropropane
- Cas Number:
- 142-28-9
- Molecular formula:
- C3H6Cl2
- IUPAC Name:
- 1,3-dichloropropane
- Test material form:
- liquid
Constituent 1
Test organisms
- Test organisms (species):
- Pimephales promelas
Study design
- Water media type:
- freshwater
Results and discussion
Effect concentrations
- Key result
- Duration:
- 14 d
- Dose descriptor:
- other: MATC
- Remarks:
- similar to NOEC
- Effect conc.:
- >= 8 - <= 16 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- larval development
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- MATC (Maximum acceptable toxicant concentration), which is similar to a NOEC, was 8 to 16 mg/l.
- Executive summary:
In an early life stage toxicity according to a US EPA national method, similar to OECD Guideline 210 (Fish, Early-Life Stage Toxicity Test), the MATC (Maximum acceptable toxicant concentration), which is similar to a NOEC, was 8 to 16 mg/l.
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