Registration Dossier
Registration Dossier
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EC number: 406-690-3 | CAS number: 43136-14-7 MDI/ODA
Endpoint summary
Administrative data
Description of key information
An acute oral toxicity study was performed with the test item with Wistar rats. The results from this study showed no evidence of acute toxicity at the only dose tested (5000 mg/kg test item). In an acute dermal toxicity study, there was no evidence of acute toxicity at the only concentration tested (2000 mg/kg test item).
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 5 000 mg/kg bw
- Quality of whole database:
- The study is a guideline study that has previously been submitted for regulatory purposes; and therefore is deemed acceptable for evaluation.
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
- Quality of whole database:
- The study is a guideline study that has previously been submitted for regulatory purposes; and therefore is deemed acceptable for evaluation.
Additional information
Justification for classification or non-classification
The oral and dermal LD50 values are greater than 2000 mg/kg bw in all studies conducted with the test item, therefore, existing data supports the justification for non-classification. Additionally the test item does not have a harmonised human health classification.
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