Registration Dossier

Administrative data

Description of key information

Skin irritation/skin corrosion: No corrosive or irritant properties 
Eye irritation: No corrosive or irritant properties

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

An in vivo study was performed to assess the acute skin irritation/corrosion of the test item. Therefore the

est item was applied, as supplied, at the dose of 0.5 g, under semi-occlusive dressing

during 4 hours on an undamaged skin area of three New Zealand rabbits.

No cutaneous reactions (erythema and oedema) were observed whatever the examination time (1, 24, 48 and 72 hours).

An in vivo study was performed to assess the acute eye irritation/corrosion of the test item.

The ocular conjunctivae reactions observed during the study have been slight and rapidly reversible in the three animals: a slight redness was noted only 1 hour after the test item instillation assoeiated a slight chemosis in two animals only 1 hour after the test item instillation.

Justification for classification or non-classification

not to be classified according to directive EC No. 1272/2008.