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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Remarks:
Type of genotoxicity: gene mutation
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2001
Report date:
2001

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 471 (Bacterial Reverse Mutation Assay)
Qualifier:
according to guideline
Guideline:
EPA OPPTS 870.5100 - Bacterial Reverse Mutation Test (August 1998)
Qualifier:
according to guideline
Guideline:
EU Method B.13/14 (Mutagenicity - Reverse Mutation Test Using Bacteria)
GLP compliance:
yes (incl. QA statement)
Type of assay:
bacterial reverse mutation assay

Test material

Constituent 1
Reference substance name:
6-Chlorbenzoxazol
IUPAC Name:
6-Chlorbenzoxazol
Constituent 2
Chemical structure
Reference substance name:
6-chloro-1,3-benzoxazole
EC Number:
607-145-4
Cas Number:
227197-72-0
Molecular formula:
C7H4ClNO
IUPAC Name:
6-chloro-1,3-benzoxazole

Results and discussion

Applicant's summary and conclusion

Conclusions:
In the absence and in the presence of the metabolic activation syystem 6-Chlorobenzoxazole did not result in relevant increases in the number of revertants in any of the bacterial strains.