Registration Dossier
Registration Dossier
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EC number: 607-145-4 | CAS number: 227197-72-0
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
- Report date:
- 2001
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- Qualifier:
- according to guideline
- Guideline:
- EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 6-Chlorobenzoxazol
- IUPAC Name:
- 6-Chlorobenzoxazol
- Reference substance name:
- 6-chloro-1,3-benzoxazole
- EC Number:
- 607-145-4
- Cas Number:
- 227197-72-0
- Molecular formula:
- C7H4ClNO
- IUPAC Name:
- 6-chloro-1,3-benzoxazole
- Details on test material:
- Purity: 98.6% GC (a/a)
Constituent 1
Constituent 2
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
Test system
- Type of coverage:
- semiocclusive
- Preparation of test site:
- clipped
- Vehicle:
- other: sesame oil
- Duration of treatment / exposure:
- 4h
- Observation period:
- 72h
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Time point:
- other: 24h, 48h, 72h
- Score:
- 0
- Reversibility:
- fully reversible within: 1d
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Based on the results of this study 6-Chlorobenzoxazole is not irritating to skin according to the classification criteria of Directive 93/21/EEC.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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