Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2001
Report date:
2001

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 401 (Acute Oral Toxicity)
GLP compliance:
yes (incl. QA statement)
Test type:
standard acute method

Test material

Constituent 1
Reference substance name:
6-Chlorbenzoxazol
IUPAC Name:
6-Chlorbenzoxazol
Constituent 2
Chemical structure
Reference substance name:
6-chloro-1,3-benzoxazole
EC Number:
607-145-4
Cas Number:
227197-72-0
Molecular formula:
C7H4ClNO
IUPAC Name:
6-chloro-1,3-benzoxazole
Details on test material:
Purity: 98.6% GC(a/a)

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
male/female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
other: sesame oil

Results and discussion

Effect levels
Sex:
female
Dose descriptor:
LD50
Effect level:
791.3 mg/kg bw
Based on:
test mat.
95% CL:
425.6 - 1 212

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The LD 50 value of the test item has been determined to be 791 mg/kg bw. for femal rats.