Registration Dossier
Registration Dossier
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EC number: 607-145-4 | CAS number: 227197-72-0
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in vivo (non-LLNA)
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
- Report date:
- 2001
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 406 (Skin Sensitisation)
- Qualifier:
- according to guideline
- Guideline:
- EU Method B.6 (Skin Sensitisation)
- GLP compliance:
- yes (incl. QA statement)
- Type of study:
- guinea pig maximisation test
Test material
- Reference substance name:
- 6-chloro-1,3-benzoxazole
- EC Number:
- 607-145-4
- Cas Number:
- 227197-72-0
- Molecular formula:
- C7H4ClNO
- IUPAC Name:
- 6-chloro-1,3-benzoxazole
- Details on test material:
- Purity: 98.6 % GC(a/a)
Constituent 1
In vivo test system
Test animals
- Species:
- guinea pig
- Strain:
- other: Pirbright-White
- Sex:
- female
Study design: in vivo (non-LLNA)
Induction
- Route:
- intradermal
- Vehicle:
- other: sesame oil
Challenge
- Route:
- epicutaneous, occlusive
- Vehicle:
- other: sesame oil
- Positive control substance(s):
- yes
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- not sensitising
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Based on the result of this study 6-Chlorobenzoxazole showed no evidence for sensitizing properties according to the classification criteria of Directive 93/21/EEC.
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