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EC number: 413-110-2
CAS number: 135861-56-2
Maximum concentration not causing irritating effects in preliminary
Signs of irritation during induction: well defined erythema was noted at
the intradermal induction sites of all test group animals at the 24 and
48 -hour observations.
Very slight erythema was noted at the intradermal induction sites of all
control group animals at the 24 -hour observation and in four control
group animals at the 48 -hour observation.
Very slight to well-defined erythema was noted at the induction sites of
all test group animals at the 1 -hour observation with very slight
erythema at the induction sites of nine test group animals at the 24
Bleeding from the intradermal industion sites was noted in five test
group animals at the 1 -hour observation. Residual test material was
noted in all test group animals. Bleeding from the intradermal induction
sites was noted in one control group animal at the 1 -hour observation.
No signs of erythema or oedema were noted at the treatement sites of
control group animals at the 1 and 24 -hour observations.
Evidence of sensitisation of each challenge concentration:
Number of animals showing evidence of sensitisation at each challenge
Other observations: bodyweight gains of animals in the test group,
between day 0 and day 24, were comparable to those in hte control group.
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