Registration Dossier

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
The information of this endpoint has been provided by ECHA as a result of an inquiry, thus the full access to data in the report is not accessible to the registrant. However the reliability is estimated to be at level 1: Study conducted in accordance with generally accepted scientific principles. Possible deficiencies do not affect the quality of relevant results.

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed
Year:
1998
Report Date:
1998

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: 92/69/EEC, C3
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Details on test solutions:
Identity and concentration of auxiliary solvent for dispersal: dimethylformamide

Test organisms

Test organisms (species):
Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)

Study design

Limit test:
yes
Total exposure duration:
72 h

Results and discussion

Effect concentrationsopen allclose all
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
> 0.08 mg/L
Basis for effect:
biomass
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
>= 0.08 mg/L
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
>= 0.08 mg/L
Basis for effect:
biomass
Details on results:
%Concentration loss over test: ... 21

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
There were limited data available on the study details. The 72 h ErC50value of the test substance on Desmodesmus subspicatus was 0.08 mg/L (growth rate), and 72 h NOEC values (biomass and growth rate) were also >= 0.08 mg/L, the highest attainable test concentration due to the limited solubility of the test material and using dimethylformamide as an auxiliary solvent.
Executive summary:

As the study was conducted under GLP and the study was already assessed by authorities, it was considered valid. The 72 h ErC50value of the test substance on Desmodesmus subspicatus was 0.08 mg/L, the highest attainable test concentration due to the limited solubility of the test material and using dimethylformamide as an auxiliary solvent. The test method was an EU C.3 limit test under GLP. The 72 h NOEC (biomass) was >= 0.0.8 mg/L, the highest attainable concentration using solvent, indicating no acute toxicity at levels up to water solubility. Concentrations were confirmed analytically. The study was selected as key.