Registration Dossier

Administrative data

Endpoint:
toxicity to microorganisms
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
The information of this endpoint has been provided by ECHA as a result of an inquiry, thus the full access to data in the report is not accessible to the registrant. However the reliability is estimated to be at level 1: Study conducted in accordance with generally accepted scientific principles. Possible deficiencies do not affect the quality of relevant results.

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed
Year:
1998
Report Date:
1998

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: "Biodegradation Activated Sludge Respiration Inhibition test" of Commission Directive 87/302/EEC (OEC No. 209)
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Test organisms

Test organisms (species):
activated sludge

Study design

Test type:
other: aerobic
Water media type:
not specified
Limit test:
yes
Total exposure duration:
3 h

Results and discussion

Effect concentrationsopen allclose all
Duration:
3 h
Dose descriptor:
IC50
Effect conc.:
> 1 000 mg/L
Duration:
3 h
Dose descriptor:
NOEC
Effect conc.:
100 mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
There were limited data available on the details. The 3 h IC50 value of the test substance on activated sludge microbes under aerobic conditions was > 1000 mg/L and a 3 h NOEC 100 mg/L.
Executive summary:

As the study was performed under GLP and assessed by authorities, it was considered as valid. The 3 h NOEC of the test substance on the activated sludge microbes under aerobic conditions was 100 mg/L. The value was created for the chemical safety assessment, where needed, for this insoluble test substance.