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EC number: 252-744-2
CAS number: 35836-73-8
Reliable acute studies based on
international guidelines are available for the three aquatic trophic
levels (fish, algae and aquatic invertebrates) and for activated sludge.
Among the data available, a toxic effect was
observed for these three aquatic trophic levels. The most sensitive
species appears to be the fish Danio rerio with a 96-hour LC50 for Nopol
of 11.1 mg/L based on nominal concentrations. For the aquatic
invertebrate Daphnia magna, the 48h-EC50 of Nopol was of 28.8 mg test
item.L-1 based on nominal concentrations and for aquatic algae, the
72-hour EC50 of Nopol to P. subcapitata for the parameters growth rate
was 21.14 mg/L.
The effects of a chronic exposure to test
item NOPOL on the reproduction of Daphnia magna was investigated
in a study conducted according to OECD Guideline 211. Under the
experimental conditions and after 21 days, the NOEC value estimated for
the most sensitive endpoint cumulative number of offspring was 0.4 mg
Finally, it has been determined that the
test substance Nopol is not harmful to activated sludge.
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