Registration Dossier
Registration Dossier
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EC number: 410-400-0 | CAS number: 88671-89-0 SYSTHANE TECHNICAL
Endpoint summary
Administrative data
Description of key information
Acute toxicity tests in rainbow trout, bluegill sunfish and sheepshead minnow produced LC50 values of 2.0, 4.4 and 5.3 mg/L, respectively. Respective NOEC values were 1.8, 2.6 and 0.91 mg/L. A 21-day prolonged exposure of rainbow trout to myclobutanil produced an LC50 >0.20 mg a.s./L, the highest concentration tested. The NOEC for this study was 0.20 mg/L.
An early life stage study with fathead minnow produced a NOEC value of 1.0 mg/L. Toxicity to invertebrates was similar to that seen in fish. A Daphnia magna acute toxicity test produced an EC50 of 17 mg/L and a NOEC of 3.2 mg/L. Toxicity was greater to the saltwater crustacean, Americamysis bahia, with an EC50 value of 0.24 mg/L and a NOEC of 0.043 mg/L. An acute toxicity test with eastern oysters produced an EC50 of 0.72 mg/L.
Chronic testing with Daphnia magna produced an EC50 >1.0 mg/L and a NOEC of 1.0 mg/L. An acute study with the midge, Chironomus riparius, produced an EC50 value of 10.5 mg/L. The NOEC for inhibitory effects on development and emergence of the midge, Chironomus riparius, was 5.0 mg/L. The EC50 was 7.8 mg/L.
The toxicity of myclobutanil was evaluated in two species of algae (Pseudokirchneriella subcapitata and Scenedesmus subspicatus). Pseudokirchneriella was the most sensitive species with a 120-hour EC50 value of 0.91 mg/L.
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