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Diss Factsheets
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EC number: 465-100-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_physical-and-chemical-properties.png)
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2005
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 005
- Report date:
- 2005
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Principles of method if other than guideline:
- The vapour pressure is estimated in MPBPWIN by three methods; all three methods use the
boiling point. The first is the Antoine method (see Chapter 14 of W.J. Lyman's book
"Handbook of Chemical Property Estimation Methods", Washington, DC, American Chemical
Society, 1990). The second is the modified Grain method (see page 31 of Neely and Blau's
Environmental Exposure from Chemicals, Volume I, CRC Press, 1985). The third is the
Mackay method (see page 31-2 of Neely and Blau's Environmental Exposure from
Chemicals, Volume I, CRC Press, 1985). For solids, a melting point is required to adjust the
vapour pressure from a super-cooled liquid to a solid. The preferred vapour pressure (VP)
method for solids, according to the designer of the program, is the Modified Grain method,although the Antoine method in this program is nearly as good because it uses the exact same methodology to convert super-cooled VP to solid VP. The Mackay method is not as applicable to as many chemical classes as the other methods, so it is generally not preferred. The hydrochloride of the base is considered to have a lower vapour pressure than the base. Therefore the base and the hydrochloride was calculated. - GLP compliance:
- yes
- Type of method:
- other: Atom/fragment contribution method using the software MPBPWIN Version v1.40©2000, provided by U.S. Environmental Protection Agency. (Modified Grain Method)
Test material
- Test material form:
- solid: particulate/powder
- Details on test material:
- Batch number: 022401
Constituent 1
- Specific details on test material used for the study:
- Not applicable as calculation method was used, The MPBWIN requires only a chemical structure to make the prediction on Vapour pressure.
Results and discussion
Vapour pressure
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- < 0 Pa
- Remarks on result:
- other: First vapour pressure
Applicant's summary and conclusion
- Conclusions:
- The calculated vapour pressure for the base of the test
substance is 4.1 * 10-11 Pa at 25°C.
For the test substance as a hydrochloride a vapour
pressure of 1.5 * 10-18 Pa at 25°C was calculated.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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