Registration Dossier
Registration Dossier
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EC number: 201-854-9 | CAS number: 88-73-3
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: migrated IUCLID4 data set
Data source
Reference
- Reference Type:
- publication
- Title:
- No information
- Author:
- Linch, A.L.
- Year:
- 1 974
- Bibliographic source:
- Am. Ind. Hyg. Assoc. J. 35, 426-432
Materials and methods
Test material
- Reference substance name:
- 1-chloro-2-nitrobenzene
- EC Number:
- 201-854-9
- EC Name:
- 1-chloro-2-nitrobenzene
- Cas Number:
- 88-73-3
- Molecular formula:
- C6H4ClNO2
- IUPAC Name:
- 1-chloro-2-nitrobenzene
Constituent 1
Results and discussion
Any other information on results incl. tables
Based on clinical and laboratory evaluation of cyanosis cases during a 10-year period a number of cyanogenic aromatic nitro compounds were ranked in descending order of relative hazard relating to their cyanogenic potential observed in exposed industrial workers (rank 1 = most potent, rank 13 = least potent):
o-chloronitrobenzene was classified in rank 7;
laboratory evaluation showed that total oxygenatable haemoglobin in some cases, notably after be expected from methaemoglobin analysis (unspecified route of absorption)
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
