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EC number: 231-323-7
CAS number: 7492-66-2
In Combined reproductive/developmental
toxicity screening test, Sprague-Dawley female rat were treated with
1,1-diethoxy-3,7-dimethylocta-2,6-diene in the concentration of 0, 125,
250 and 500 mg/kg-day orally by gavage in Corn oil or methylcellulose.
Clinical signs and lower body weights and body weight gains were
observed at 250 and 500 mg/kg-day as controls. In addition, no
reproductive toxicity was observed in treated female rats at 125, 250
and 500 mg/kg-day. But, developmental toxicity was observed as decrease
in pups body weight at 500 mg/kg-day. Therefore, NOAEL was considered to
be 500 mg/kg-day for p genearrtion and 250 mg/kg-day for F1 generation
when Sprague-Dawley female rat were treated with
1,1-diethoxy-3,7-dimethylocta-2,6-diene orally by gavage for approx 46
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