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EC number: 700-736-9
CAS number: 2149571-40-2
LC50, 96 hours, Oncorhynchus mykiss = 0.544 mg/L
NOEC, 96 hours, Oncorhynchus mykiss = 0.401 mg/L
An acute toxicity study (Envigo, 2016) was conducted to assess the
toxicity of the test substance MTF to fish. The study was conducted
according to OECD test guideline 203 and EC test guideline C1 and in
compliance with GLP.
Groups of 7 rainbow trout (Oncorhynchus mykiss) per dose group were
exposed to test media containing MTF under semi-static conditions (daily
medium renewal) for 96 hours. Nominal test material concentrations were
0.0950, 0.209, 0.460, 1.01, 2.23 and 4.90 mg/L; control and solvent
control groups were also exposed concurrently with the treated dose
groups. Test material concentrations were determined by Gas
Chromatography with mass Spectrometric detection; the resulting effect
concentrations (LC50, NOEC) are quoted in terms of the measured
Based on mean measured concentrations, the 96 hour LC50 was 0.544 mg/L
(95% confidence limits of 0.480 and 0.643 mg/L), and the no observed
effect concentration was 0.401 mg/L.
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