Registration Dossier
Registration Dossier
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EC number: 248-145-0 | CAS number: 26966-75-6
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
A study performed with an 80:20 mixture of 2,4- and 2,6-TDA was carried out according to OECD guideline 209 and gave a 3h EC50 > 100 mg/l. It is expected that ortho-TDA would behave similarly. 2,4-TDA is a structural isomer of o-TDA, differing in the substitution pattern of the amine groups on the tolyl ring; having similar physical chemical properties; similar environmental fate; and similar health effects (acute toxicity and genotoxicity). As a result, data from 2,4 -TDA can be used for read across to 2,3- TDA.
Key value for chemical safety assessment
Additional information
The studies with 2,3-TDA and 3,4-TDA use the marine bacteria Vibrio fischeri under saline conditions and therefore have little relevance to sewage treatment plants.
The experimental study with an 80:20 mixture of 2,4- and 2,6-TDA (Caspers et al.) was carried out according to OECD guideline 209 and gave a 3h EC50 > 100 mg/l. It is expected that ortho-TDA would behave similarly.
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