Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Tests are available for prolonged exposure of algae, invertebrates and fish. These studies were fully reported and conducted according to GLP requirements. The short-term values for fish and Daphnia were derived from the long term studies. It should be noted that the test animals were fed during the test. Additional data for short-term for marine species were taken from the EU Risk Assessment Report (2008) as these values were below the data for fish and Daphnia.

No specific toxicity tests on micro-organisms were conducted, but in the biodegradation test, no inhibition was observed up to 30 mg/l. The NOEC is set to 22 mg/l, which is far above the water solubility of AHTN.

 

Species

Guideline

Result (mg/l)

Reference

Remarks

Algae

 

 

 

 

Pseudokirchneriella subcapitata

OECD 201

72h-ECr50 > 0.835 72h-NOECr = 0.40

Van Dijk 1997

Rel. 1

 

 

 

 

 

Invertebrates

 

 

 

 

Nitocra spinipes

(marine)

 

96h-LC50 = 0.61

Breitholz et al 2003, in EU RAR 2008

Rel. 2 for the short-term part

Acartia tonsa

(marine)

draft ISO/DIS 14669

48h-LC50 = 0.71

Wollenberger et al 2003, in EU RAR 2008

Rel. 2 for the short-term part

Acartia tonsa

(marine)

OECD draft

6d-EC10, larval dev. ratio = 0.028, NOEC = 0.022

Bjornestad 2007

Rel. 1

Daphnia magna

OECD 202

3d-EC50 imm. > 0.80

Wütrich 1996a

Rel. 2

 

OECD 202

21d-NOECrepr = 0.196

Wütrich 1996a

Rel. 1

 

 

 

 

 

Fish

 

 

 

 

Lepomis macrochirus

OECD 204

4d-LC50 = 1.49

Wütrich 1996b

Rel. 2

 

OECD 204

21d-NOECgrowth = 0.089

Wütrich 1996b

Rel. 1

Pimephales promelas

OECD 210

36d-NOEC = 0.035

Croudace et al 1997

Rel. 1

Brachydanio rerio

OECD 210

34d-NOEC = 0.035

Hooftman et al 1999

Rel. 1

         
 Plants        
 

Dicotyledonous species: Beta vulgaris (sugar beet), Brassica napus

(rape), Lycopersicon esculentum (tomato), Pisum sativum (pea)

Monocotyledonous species: Allium cepa (onion), Lolium perenne

(perennial ryegrass)

 OECD 208  21d NOEC <0.198 mg of act. ingr./kg soil dw (most sensitive species: Beta vulgaris)  Rippergen 2018  Rel. 1
Soil (nitrogen transformation)   OECD 2016 28d NOEC≥31.6 mg act. ingr. /kg soil dw  Hauser 2017  Rel.1