Registration Dossier

Administrative data

Endpoint:
toxicity to microorganisms
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
The authors tested the toxicity to micro-organisms of benzal chloride using a methodology described by Krebbs (1983). GLP standards are not specified and very few data are given concerning the materials and methods and the results. Thus the study is considered as not assignable, such a Klimisch 4e, since the documentation is insufficient for assessment.

Data source

Reference
Reference Type:
publication
Title:
Versuche zur biologischen Abbaubarkeit chlororganischer Verbindungen
Author:
Steinhäuser K.G., Amann W. and Polenz A.
Year:
1986
Bibliographic source:
Vom Wasser, 67: 147-154

Materials and methods

Principles of method if other than guideline:
Krebs F. (1983) Toxizitätstest mit gefriergetrockneten Leuchtbakterien. Gewässerschutz, Wasser, Abwasser 63: 173-230
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Benzylidenchlorid
No more data available

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
Photobacterium phosphoreum

Study design

Test type:
static
Water media type:
not specified
Limit test:
no
Total exposure duration:
30 min

Results and discussion

Effect concentrations
Duration:
30 min
Dose descriptor:
EC50
Effect conc.:
32 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
other: bioluminescence

Applicant's summary and conclusion

Validity criteria fulfilled:
not applicable
Conclusions:
The authors tested the toxicity of benzal chloride using a methodology described by Krebbs (1983). Under these test conditions the EC50 for Photobacterium phosphoreum was assessed to be 32 mg/L.
Executive summary:

The authors tested the toxicity of benzalchloride using a methodology described by Krebbs (1983). Photobacterium phosphoreum was exposed to the test substance and after 30 min of exposure bioluminescence was measured using a Beckman-Microtox-photometer. The EC50 was assessed to be 32 mg/L. No further details on the materials and methods and on the results are available.

GLP standards are not specified and very few data are given concerning materials and methodology and results. Thus the study is considered not assignable due to insufficient data for assessment.