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Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 21 May 2012 to 24 August 2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
2012-12-15
Type of method:
differential scanning calorimetry
Key result
Boiling pt.:
311.6 °C
Atm. press.:
1 013.25 hPa

Five assays were performed during the test, the temperature values obtained for the corrected boiling point varied between 305.8 and 313.9 °C. The mean value for the boiling point is explained as the mean of at least two assays for which the the boiling point value are in the range of the estimated accuracy of the method: ± 0.5 °C up to 326.9 °C and ± 2.0 °C above 326.9 °C.

The assays No. 3 and 5 were taken into account for the boiling point.

Assay

Atmospheric pressure (kPa)

Crucible used

Mass of test item

Programmation

Observed temperature of boiling (°C)

Corrected

temperature

of boiling

(°C) 

1

98.3

Aluminium, 120 μL, with pierced lid

5.38 mg

Isotherm at 25 °C for 2 min

Heating phase from 25 to 500 °C at 20 °C/min

Cooling phase from 500 to 25 °C at 50 °C/min

Isotherm at 25 °C for 10 min

304.3

2

98.3

11.84 mg

Isotherm at 25 °C for 2 min

Heating phase from 25 to 400 °C at 10 °C/min

Cooling phase from 400 to 25 °C at 50 °C/min

Isotherm at 25 °C for 10 min

312.4

3

98.0

9.25

Isotherm at 25 °C for 2 min

Heating phase from 0 to 400 °C at 10 °C/min

Cooling phase from 400 to 25 °C at 50 °C/min

Isotherm at 25 °C for 10 min

310.1

311.7 

4

98.0

10.10

Isotherm at 25 °C for 10 min

Heating phase from 0 to 400 °C at 10 °C/min

Cooling phase from 400 to 25 °C at 50 °C/min

Isotherm at 25 °C for 10 min

311.5

 -

5

98.0

8.08

Isotherm at 25 °C for 10 min

Heating phase from 25 to 400 °C at 10 °C/min

Cooling phase from 400 to 25 °C at 50 °C/min

Isotherm at 25 °C for 10 min

309.8

 311.4
Conclusions:
The mean corrected boiling point of the test item was: 311.6 ± 0.5 °C.
Executive summary:

The boiling point of the REACh substance (2-Hydroxy-3-sulphopropyl) dimethyl[3-[(1-oxododecyl) amino]propyl]ammonium hydroxide (EC 242-893-1) was investigated in a GLP-compliant study performed in accordance with OECD Guideline 103 (Boiling point/boiling range) and EU Method A.2 (Boiling Temperature). The mean boiling point of the test item was 311.6 ± 0.5 °C.

Description of key information

The boiling point of the REACh substance (2-Hydroxy-3-sulphopropyl) dimethyl[3-[(1-oxododecyl) amino]propyl]ammonium hydroxide (EC 242-893-1) was investigated in a GLP-compliant study (Ferron, 2012) performed in accordance with OECD Guideline 103 (Boiling point/boiling range) and EU Method A.2 (Boiling Temperature). The mean boiling point of the test item was 311.6 ± 0.5 °C.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
311.6 °C

Additional information

The boiling point of the substance EC 242-893-1 was investigated in a GLP-compliant study (Ferron, 2012) performed in accordance with standard methods, without deviations. The study is considered as reliable (Klimisch 1) and was selected as key study for the endpoint.