Registration Dossier
Registration Dossier
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EC number: 230-898-1 | CAS number: 7360-53-4
Endpoint summary
Administrative data
Description of key information
Acute oral toxicity: OECD420, EU method B.1 bis: LD50 >2000 mg/kg body weight
Acute inhalation toxicity: OECD 403, EU method B.2: LC50 >2.51 mg/L (highest tchnically feasible dust concentration)
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Dose descriptor:
- LC50
- Value:
- 2 510 mg/m³ air
Additional information
Acute oral toxicity: The LD50 was >2000 mg/kg body weight. No classification is therefore derived.
Acute inhalation toxicity: The LC50 was >2.51 mg/L which was the highest technically feasible concentration of the generated dust.
Justification for classification or non-classification
No classification is derived for acute toxicity after oral administration, as the LD50 was <2000 mg/kg body weight.
The acute toxicity via inhalation yielded a LC50/4h of >2.51 mg/L. 2.51 mg/L was the highest technically reproducible dust concentration in that experiment. In a preliminary experiment, however, animals had to be sacrificed as moribund after having been exposed to slightly higher test substance concentrations. Therefore it is assumed that the LC50/4h is close to 2.51 mg/L and in each case below 5 mg/L. Although respirable dust fractions at higher concentrations may not be technically producible, the classification derived is "Harmful by inhalation".
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