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EC number: 931-801-1
CAS number: -
The substances erucamide and stearmide, witch are structurally and composition related to oleamide, were tested (Guideline Study conducted to GLP). Based on the analogy it can be concluded that oleamide is also readily biodegradable.
Two studies investigating the ready
biodegradability of the structural related substances erucamide and
stearmide were available. The tests were carried out according to the
OECD Guideline No. 301B: Ready Biodegradability: CO2 Evolution Test
(1992), under GLP conditions. Both substances reached a biodegradation
value of > 60% after 28 days. However, the degradation values of 62 %
and 64 % were not reached within the 10-d window, but as the substances
are a mixture of constituents with different chain-lengths, sequential
biodegradation of the individual structures is taking place. Due to a
degradation of > 60% within 28 days erucamide and stearmide can be
regarded as readily biodegradable. The 10 -day window should not be
applied to interpret the test results (Annex I, OECD Guideline for The
Testing of Chemicals 'Revised introduction to the OECD guidelines for
testing of chemicals, section 3', OECD, March 2006). An additional
calculation was used to investigate the biodegradation of oleamide. A
QSAR prediction with SRC BIOWIN v4.10 also indicate that the substance
is readily biodegradable. The calculation is scientifically accepted and
reliable, further information will not be required for the assessment
and based on read across to the structural related substances erucamide
and stearmide and the ready biodegradability prediction from QSAR,
oleamide can be regarded as readily biodegradable.
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