Chloramide

Ecotoxicological Summary

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:

PNEC aqua (freshwater)

PNEC value:

0.98 µg/L

Assessment factor:

10

Extrapolation method:

assessment factor

Marine water

Hazard assessment conclusion:

no hazard identified

STP

Hazard assessment conclusion:

no emission to STP expected

Sediment (freshwater)

Hazard assessment conclusion:

no exposure of sediment expected

Sediment (marine water)

Hazard assessment conclusion:

no exposure of sediment expected

Hazard for air

Air

Hazard assessment conclusion:

no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:

PNEC soil

PNEC value:

0.181 µg/kg soil dw

Extrapolation method:

equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:

no potential for bioaccumulation

Conclusion on classification

Based on the available data, monochloramine is considered as rapidly degradable and not potentially bioaccumulable.

 

1)     Classification and labelling for monochloramine as pure substance:

 

1.1) According to the DSD Regulation, Directive 67/548/EC

Acute toxicity:

The lowest L(E)C50s obtained were between 0.01 and 1 mg/L. The lowest L(E)C50 was 11.8 µg/L for theC. dubia(Farrell et al 2001).

Therefore, the monochloramine is considered to be “very toxic to the aquatic organisms”.

Monochloramine is classified as :R50 "very toxic to aquatic organisms" and labelled N.

Chronic toxicity:

Monochloramine is not classified as hazardous to the aquatic environment since it is considered as rapidly degradable and not potentially bioaccumulable.

Monochloramine is classified as: not classified

 

1.2) According to the CLP Regulation, Regulation (EC) No 1272/2008,

Acute toxicity:

The lowest L(E)C50s obtained were between 0.01 and 1 mg/L. The lowest L(E)C50 was 11.8 µg/L for theC. dubia (Farrell et al 2001).

Therefore, the monochloramine is considered to be “very toxic to the aquatic organisms”.

Monochloramine is classified as:"acute env. tox. cat. 1" and labelled "H400; Very toxic to aquatic life» and with an M-Factor of 10.

Chronic toxicity:

For CLP regulation,classification is based on the lowest EC10 obtained on Danio rerio and on the rapid degradability and not potentially bioaccumulable properties.The lowest EC10 was 9.8 µg/L (Daniel Gilberg (2012)). Thus,monochloramine is considered to be “very toxic to the aquatic life with long lasting effect”

Monochloramine is classified as:"Chronic env. tox. cat. 1» and labelled "H410 Very toxic to aquatic life with long lasting effect ") and with an M-factor of 1.

 

 

 

Overview of classification and labellingfor monochloramine as pure substance

In a context of DSD regulation,Directive 67/548/EC: N;R50

In the context of CLP regulation: Regulation (EC) No 1272/2008:

-         “acute env. tox. cat. 1" and labelled "H400; Very toxic to aquatic life» and with an M-Factor of 10.

-         “Chronic env. tox. cat. 1» and labelled "H410; Very toxic to aquatic life with long lasting effect» and with an M-factor of 1.

 

 

2)     Classification and labelling for a mixture of monochloramine of concentration between 1% (10 g/L) and 0.25% (2.5 g/L):

 

2.1) According to the DPD Regulation, Directive 1999/45/EC:

Acute toxicity:

The mixture at 1% of monochloramine contain less than 2.5% (classification threshold for 0.01 < L(E)C50=0.0118 mg/L ≤ 0.1)of ingredient classified as very toxic to aquatic organisms (N ; R50), therefore the mixture at 1% of monochloramine is not classified for acute toxicity.

 

Chronic toxicity :

As monochloramine as pure substance is not classified for chronic toxicity, the mixture at 1% of monochloramine is not classified for chronic toxicity

 

2.2) According to the CLP Regulation, (EC) No 1272/2008 (CLP):

 Classification was performed with the summation method.

 

Acute toxicity:

The sum of the concentration in % of the ingredient classified as acute Category 1 x M has to be ≥ 25% :

                              1% x 1 = 1% i.e. < 25%, thus the mixture is not classified for acute toxicity.

 

Chronic toxicity :

-         The sum of the concentration in % of the ingredient classified as chronic Category 1 x M has to be ≥ 25%: 

               1% x 1 = 1% i.e. < 25%, thus the mixture is not classified as chronic toxicity category 1.

 

-         (M x 10 x sum in % of the ingredient classified as chronic Category 1) + sum in % of the ingredient classified as chronic Category 2 has to be ≥ 25%:  

               (1 x 10 x 1%) + 0 = 10% i.e. <25%, thus the mixture is not classified as chronic toxicity category 2.

 

Formixture of monochloramineconcentration at 1%

-         (M x 100 x sum in % of the ingredient classified as chronic Category 1) + (10 x sum in % of the ingredient classified as chronic Category 2) + sum in % of the ingredient classified as chronic Category 3 has to be ≥ 25%:  

              (1 x 100 x 1%) + 0 + 0 = 100% i.e. ≥ 25%, thus the mixture is classified as chronic toxicity category 3.

 

For mixture of monochloramineconcentration at 0.25%

-          (M x 100 x sum in % of the ingredient classified as chronic Category 1) + (10 x sum in %of the ingredient classified as chronic Category 2) + sum in % of the ingredient classified as chronic Category 3 has to be ≥ 25%:  

              (1 x 100 x 0.25%) + 0 + 0 = 25% i.e. ≥ 25%, thus the mixture is classified as chronic toxicity category 3.

 

 

Overview of classification and labellingfor a mixture of monochloraminebetween 1% and 0,25%:

In a context of DPD regulation,1999/45/EC: not classified

In the context of CLP regulation: Regulation (EC) No 1272/2008:

-         "Chronic env. tox. cat. 3" ("H412; harmful to aquatic life with long lasting effect ")

 

3)     Classification and labelling for a mixture of monochloramine at less or equal to 0 .0003% (

≤

3 mg/L):

 

3.1) According to the DPD Regulation, Directive 1999/45/EC:

Acute toxicity:

The mixture at 0.0003% of monochloramine contain less than 2.5% (since 0,01 < L(E)C50=0.0118 mg/L ≤ 0,1) of ingredient classified as very toxic to aquatic organisms(N ; R50), thereforethe mixture at 0.025% of monochloramine is not classified for acute toxicity.

 

Chronic toxicity:

As monochloramine as pure substance is not classified for chronic toxicity, the mixture at 1% of monochloramine is not classified for chronic toxicity

 

3.2) According to the CLP Regulation, (EC) No 1272/2008 (CLP):

 Classification was performed with the summation method.

 

Acute toxicity:

The sum of the concentration in % of the ingredient classified as acute Category 1 x M has to be ≥ 25%:

               0.0003% x 10= 0.003% i.e. < 25%, thus the mixture is not classified for acute toxicity.

 

Chronic toxicity :

-         The sum of the concentration in % of the ingredient classified as chronic Category 1 x M has to be ≥ 25%: 

              0.0003% x 1 = 0.0003% i.e. < 25%, thus the mixture is not classified as chronic toxicity category 1.

 

-         (M x 10 x sum in % of the ingredient classified as chronic Category 1) + sum in % of the ingredient classified as chronic Category 2 has to be ≥ 25%:  

               (1 x 10 x 0.0003%) + 0 = 0.003% i.e. < 25%, thus the mixture is not classified as chronic toxicity category 2.

 

-         (M x 100 x sum in % of the ingredient classified as chronic Category 1) + (10 x sum in % of the ingredient classified as chronic Category 2) + sum in % of the ingredient classified as chronic Category 3 has to be ≥ 25%:  

              (1 x 100 x 0.0003%) + 0 + 0 = 3% i.e.

<

25%, thus the mixture is not classified as chronic toxicity category 3.

 

Overview of classification and labellingfor a mixture of monochloramine at 0.0003%:

In a context of DPD regulation,1999/45/EC: not classified

In the context of CLP regulation: Regulation (EC) No 1272/2008: not classified