Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Short-term toxicity to fish:

The LC50 value of 1-methyl-1H-imidazole (CAS 616-47-7) on Leuciscus idus was determined to be >= 100 mg/L to <= 215 mg/L (nominal, no analytics) in a guideline study according to DIN 38 412 (BASF AG 10F0073/885186, 1989).

Therefore, the substance is considered to be with high probability acutely not harmful to fish. 

 

Long-term toxicity to fish:

No experimental data available.

In Annex IX of Regulation (EC) No 1907/2006, it is laid down that chronic tests shall be proposed by the registrant if the chemical safety assessment indicates the need to investigate further the effects on fish. According to Annex I of this regulation, the chemical safety assessment triggers further action when the substance or the preparation meets the criteria for classification as dangerous according to Directive 67/548/EEC or Directive 1272/2008 or is assessed to be a PBT or vPvB. The hazard assessment of the substance reveals neither a need to classify the substance as dangerous to the environment, nor is it a PBT or vPvB substance, nor are there any further indications that the substance may be hazardous to the environment. Therefore, and for reasons of animal welfare a chronic test on fish is not provided.

 

Short-term toxicity to aquatic invertebrates:

The acute toxicity of 1-methyl-1H-imidazole (CAS 616-47-7) to Daphnia magna was tested in a guideline study according to EU method C2. The EC0 value was determined to be 125 mg/L; the EC50 value was found to be about 267.94 mg/L after 48 h, based on nominal test concentrations (BASF AG, 1989; report no.: 1/0243/2/89-0243/89).

In conclusion, 1-methyl-1H-imidazole (CAS 616-47-7) is considered to be with high probability acutely not harmful to aquatic invertebrates. 

 

Long-term toxicity to aquatic invertebrates:

No experimental data available.

In Annex IX of Regulation (EC) No 1907/2006, it is laid down that chronic tests shall be proposed by the registrant if the chemical safety assessment indicates the need to investigate further the effects on aquatic invertebrates. According to Annex I of this regulation, the chemical safety assessment triggers further action when the substance or the preparation meets the criteria for classification as dangerous according to Directive 67/548/EEC or Directive 1272/2008 or is assessed to be a PBT or vPvB. The hazard assessment of the substance reveals neither a need to classify the substance as dangerous to the environment, nor is it a PBT or vPvB substance, nor are there any further indications that the substance may be hazardous to the environment. Therefore, a chronic test on aquatic invertebrates is not provided.

 

Toxicity to aquatic algae and cyanobacteria:

The acute toxicity of 1-methyl-1H-imidazole (CAS 616-47-7) on the aquatic green algae Desmodesmus subspicatus was investigated in a study conducted similar to OECD 201(BASF AG, 1990; report no.: 2/204389/t72).The results were recalculated using ToxRatPro v2.10 (BASF SE, 2018).After 72 h, the ErC10 was found to be 119.4 mg/L based on nominal concentrations; the 72 -h ErC50 was determined to be 202.5 mg/L.

1-methyl-1H-imidazole (CAS 616-47-7) is considered to be with high probability acutely not harmful to aquatic algae.

 

Toxicity to microorganisms:

The toxicity of 1-methyl-1H-imidazole (CAS 616-47-7) to microorganisms was investigated in a growth inhibition guideline study performed according to DIN 38412-8, using Pseudomonas putida as test organism. After 7 h of incubation, the EC10 was determined to be 589.6 mg/L (7h EC50 = 1050 mg/L), based on nominal test concentrations.

The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.