Registration Dossier

Environmental fate & pathways

Henry's Law constant

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

From the water surface the substance will slowly evaporate into the atmosphere.

Key value for chemical safety assessment

Henry's law constant (H) (in Pa m³/mol):
8.12
at the temperature of:
25 °C

Additional information

QSAR-disclaimer:

In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met.

According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labeling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided.

For the assessment of 1-methyl-1H-imidazole (CAS 616-47-7) (Q)SAR results were used for the estimation of the Henry’s Law constant. The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment.

Therefore, further experimental studies on the Henry’s Law Constant are not provided.

 

Assessment:

The Henry’s Law Constant of 1-methyl-1H-imidazole (CAS 616-47-7) was calculated by the bond estimation method of HENRYWIN v3.20 (EPISuite v 4.11) to be 8.12 Pa m³/mol. The estimation refers to the uncharged molecule. The substance is within the applicability domain of the model. Based on the calculated data, the substance is expected to evaporate slowly into the atmosphere from the water surface.