Registration Dossier
Registration Dossier
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EC number: 204-514-8 | CAS number: 122-00-9
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.031 mg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.31 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.003 mg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 10 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.214 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.021 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.025 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
- PNEC value:
- 8.37 mg/kg food
- Assessment factor:
- 300
Additional information
Aquatic PNEC values are based on the lowest LC50 value from a 72-hours static study with daphnids which was 31 mg/L. For computation of the sediment and soil PNEC values the equilibrium-partitioning method was applied. The PNEC oral was derived from the NOAEL of 251 mg/kg bw/day seen in the available 28-day oral repeated dose toxicity study. The available ecotoxicological information is sufficient to adequately characterise potential hazards of the substance to the environment. Additional ecotoxicological studies are not required.
Conclusion on classification
The substance 4'-methylacetophenone does not meet the criteria for classification as given in Commission Regulation (EU) No 286/2011 amending for the second time Regulation (EC) No 1272/2008. The substance is not to be classified for environmental hazards on the basis of the available information on ecotoxicology, environmental fate and physical-chemical properties.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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