Registration Dossier
Registration Dossier
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EC number: 204-514-8 | CAS number: 122-00-9
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The substance was moderately toxic to aquatic invertebrates in an acute test and the EC50 value was 31 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 31 mg/L
Additional information
The acute aquatic toxicity of the test substance 4'-methylacetophenone was studied under GLP in a static acute toxicity test with freshwater invertebrates (Daphnia magna) in accordance with EU Method C.2 (1992). The test substance was added to test medium (M4-medium according to Elendt) at nominal concentrations of 6.5, 13, 25, 50 and 100 mg/L. These concentrations were monitored by analysing the TOC content of each test medium at the start and end of the test. Good agreement between nominal and measured test concentrations was found and the effect levels were based on measured concentrations (arithmetic mean of concentrations at time points 0 and 24 or 48 hours). The calculated EC50 value was 31 mg/L (95% CL: 25.2 to 38.4 mg/L).
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