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EC number: 947-652-0
CAS number: 943986-70-7
2 Cumulative mortality of parental daphnids during the
Cumulative number of dead parental daphnids on day:
Table 3 Average body lengths of parental daphnids
Table 4 Overview of effect parameters
21-day LC50 (parental mortality)
NOEC for parental mortality
21-day EC50 for reproduction
21-day LOEC for reproduction
21-day NOEC for reproduction
21-day LOEC for parental body length
21-day NOEC for parental body length
In a 21 -day semi-static reproduction study, the toxicity of the test
item to aquatic invertebrate Daphnia magna was assessed according to
OECD guideline no. 211 and GLP principles. Nominal test concentrations
were prepared at a loading rate of 100 mg/L with further dilutions to
achieve the following test concentrations: 4.6, 10, 22, 46 and 100 mg/L.
Per test concentration 10 vessels were used, whereas for the control 20
vessels were used. In each vessel, one daphnid (<24 hours of age) was
placed. Every three days test solutions were renewed. The test
concentrations were analytically verified and the results showed that
the test concentrations were in agreement with nominal concentrations
(94-114%) and stable during the two or three-day refreshment periods
(98-108% of initial). There was no dose dependent effect of the test
substance on mortality, reproduction or body length of the parental
daphnids. Therefore it was concluded that the test item was not toxic
for the reproduction of Daphnia magna (NOEC 100 mg/L). All criteria for
acceptability of the test were met according to OECD guideline 211 and
the study is considered to be reliable without restrictions.
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