Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 947-652-0
CAS number: 943986-70-7
An Ames test was performed equivalent to OECD 471 guideline and GLP
In the dose-range finding study, the test item was tested up to and
including concentrations of 5000 μg/plate in strain TA100 in the
pre-incubation assay. The substance did not precipitate on the plates at
this dose level and the bacterial background lawn was not reduced at any
of the concentrations tested.
In the mutation experiments, the test item was tested up to and
including concentrations of 5000 μg/plate in the tester strains TA1535,
TA1537, TA98, TA100 and WP2uvrA in the pre-incubation assay. The test
item did not precipitate on the plates at this dose level and no
cytotoxicity was observed.
The negative and strain-specific positive control values were within the
laboratory historical control data ranges indicating that the test
conditions were adequate and that the metabolic activation system
All bacterial strains showed negative responses over the entire dose
range, i.e. no significant dose-related increase in the number of
revertants in independently repeated experiments. In conclusion, based
on the results of this study it is concluded that the substance is not
mutagenic in the Salmonella typhimurium reverse mutation assay and in
the Escherichia coli reverse mutation assay.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Sellel veebilehel kasutatakse küpsiseid, et tagada lehe parim kasutus.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again