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Toxicological information

Developmental toxicity / teratogenicity

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Administrative data

Endpoint:
developmental toxicity
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
The developmental toxicity potential has been estimated using Vega model v.1.2.2.
The complete estimation report has been attached into the IUCLID section 13..

Data source

Reference
Reference Type:
other: Estimation tool
Title:
N.A.
Author:
N.A.
Year:
2018
Bibliographic source:
N.A.

Materials and methods

Principles of method if other than guideline:
The developmental toxicity potential has been estimated using Vega model v.1.2.2.
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
(+)-tartaric acid
IUPAC Name:
(+)-tartaric acid

Test animals

Species:
other: not applicable

Results and discussion

Results: maternal animals

Effect levels (maternal animals)

Remarks on result:
other: not expected as developmental toxicant, based on QSAR estimation

Maternal abnormalities

Abnormalities:
not specified

Results (fetuses)

Effect levels (fetuses)

Remarks on result:
other: not expected as developmental toxicant, based on QSAR estimation

Fetal abnormalities

Abnormalities:
not specified

Overall developmental toxicity

Developmental effects observed:
no

Applicant's summary and conclusion