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EC number: 235-935-5
CAS number: 13052-09-0
Rabbit No and sex
Region of the eye
Hours after instillation
Average 24-48-72 hours
Degree of opacity
The potential to cause damage to the
conjunctiva, iris or cornea was assessed in three New Zealand White
rabbits, each subjected to a single ocular instillation of 0.1 ml of the
test material. Ocular reactions were assessed 1, 24, 48 and 72 hours
after treatment. Injection of the conjunctival blood vessels was
observed in all rabbits during the first hour following instillation.
Very slight discharge and very slight chemosis were also observed in two
of these rabbits at this time. The test eyes of all rabbits were overtly
normal at the 24 hour examination. Instillation of the test material
caused practically no initial pain response.
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