Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 430-610-6 | CAS number: 226996-19-6
Long-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 211 (Daphnia magna Reproduction Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
- Details on test solutions:
- Saturated test solutions with 100 mg TN-105 per litre were prepared and filtered. This nominal loading of 100 mg/l was then diluted by a factor of two to get the further nominal loadings loadings of 6.25, 12.5, 25, and 50 mg/l.
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 21 d
Test conditions
- Nominal and measured concentrations:
- Nominal loading 100 mg/L: 7.5, 3.8 and 12.4 mg/l (mean: 7.9 mg/l).
Nominal loading 50 mg/L: 3.7, 1.9 and 6.1 mg/l (mean: 3.85 mg/l)
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 21 d
- Dose descriptor:
- other: NOEL
- Effect conc.:
- 50 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks:
- TN-105 (based on diluted extracted loading)
- Basis for effect:
- reproduction
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 3.85 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Remarks:
- TN-105 (the soluble ligand only is measurable, extrapolated to test material)
- Basis for effect:
- reproduction
Applicant's summary and conclusion
- Conclusions:
- Nominal loadings up to and including 100 mg/l did not affect survival/viability). Adult growth (body length), mean cumulative reproduction, age to first brood and intrinsic rate was unaffected up to and including a nominal loading of 50 mg/l (relevant NOEL: 50 mg/l), corresponding to a measured concentration (NOEC) of 3.85 mg/l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
