Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 273-227-8
CAS number: 68953-84-4
* Micronucleated polychromatic erythrocytes - percentage compared to
DAPD was administered to mice by intraperitoneal injections at doses
that included toxic responses (lethality, behavioural effects, and
decreased PCE/NCE ratio). Erythrocytes were isolated from the femur
marrow at periods up to 72 hr post dosing. These cells were assessed for
evidence of micronuclei induction in PCEs with an increase seen only for
the positive control TEM. DAPD was not found to possess clastogenic
activity in this mouse erythropoietic cell in vivo assay for micronuclei.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again