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EC number: 273-227-8
CAS number: 68953-84-4
Test material was subjected to a guinea pig maximization sensitization
assay according to OECD and GLP guidelines. The induction phase included
both intradermal and epidermal exposures to test chemical plus adjuvant.
The dermal response following 48h after the first challenge to 25% or
100% of chemical resulted in clinical effects (edema or desquamation)
for 15% or 25% of test animals, respectively.
48 Hours after the second challenge 55% of the animals exposed to 25% of
test chemical showed signs of desquamation, edema or blanching. In the
test group exposed to 100% of test chemical, 75% of the animals showed
signs of a sensitization reaction after 48 hours.
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