Registration Dossier
Registration Dossier
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EC number: 273-227-8 | CAS number: 68953-84-4
Stability in organic solvents and identity of relevant degradation products
Administrative data
- Endpoint:
- stability in organic solvents and identity of relevant degradation products
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study design same as that used for water solubility. Conducted under GLP conditions. Limited information on stability of test substance available.
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 004
- Report date:
- 2004
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Solubility test according to the shake flask method. Sample analysis using HPLC was repeated after 7 days, thus giving an indication on the substance stability in solution in n-octanol.
- GLP compliance:
- yes
Test material
- Reference substance name:
- 1,4-Benzenediamine, N,N'-mixed Ph and tolyl derivs.
- EC Number:
- 273-227-8
- EC Name:
- 1,4-Benzenediamine, N,N'-mixed Ph and tolyl derivs.
- Cas Number:
- 68953-84-4
- Molecular formula:
- C18-20H16-20N2
- IUPAC Name:
- Reaction mass of N-phenyl,N'-o-tolyl-phenylene diamine, N,N'-diphenyl-p-phenylene diamine and N,N'-di-o-tolyl-phenylene diamine
Constituent 1
Results and discussion
- Test substance stable:
- yes
- Transformation products:
- not measured
Any other information on results incl. tables
Recovery data for test chemical in octanol showed all components were >97% recovered after 7 days.
Applicant's summary and conclusion
- Conclusions:
- The test substance is stable when dissolved in n-octanol.
- Executive summary:
For the purpose of testing the test substance's solubility in organic solvents, a solution of 1,4 -benzenediamine, N,N'-mixed Ph and tolyl derivs. in n-octanol was prepared using the shake flask method. After 24 hours the solution was analyzed using reversed phase HPLC.
Re-analysis of test solutions after 7 days showed that >97% of all measured constituents were still present in the test solution. It can thus be concluded that the test substance is stable when dissolved in n-octanol.
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