Registration Dossier
Registration Dossier
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EC number: 203-581-0 | CAS number: 108-42-9
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The lethal concentration (LC50) value of 3-chloroaniline in fish [Danio rerio (Zebra Danio)] in a 96 hr study on the basis of mortality effect was found to be 0.147 mg/L.Thus considering the CLP Criteria for aquatic classification of the substance , it is concluded that 3-chloroaniline exhibits short term toxicity to fish (Danio rerio ) in aquatic Acute Category 1.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.147 mg/L
Additional information
No. of studies were reviewed for Short-term toxicity to fish from reliable sources having Klimisch rating 2.
The summary of the results are presented below
Sr.No |
Endpoint |
Effect values |
Basis for effects |
Duration |
Species |
Sources |
1 |
LC50 |
0.147 mg/L |
Mortality |
96 hrs. |
Danio rerio |
Experimental data from Science of the Total Environment for CAS : 108-42-9 |
2 |
NOEC |
5 mg/L |
- |
24 hrs. |
Petromyzon marinus |
Experimental data from Spec.Sci.Rep.Fish.No.207 for CAS : 108-42-9 |
Based on the studies summarized in the above table for the target substance 3-chloroaniline,the endpoint value was found to vary between LC50 = 0.147 mg/L and NOEC = 5 mg/L in a 24 hrs to 96 hrs. study respectively on the basis of mortality effect. Based on the LC50 value and considering the CLP Criteria for aquatic classification of the substance , it is concluded that 3-chloroaniline exhibits short term toxicity to fish (Danio rerio and Petromyzon marinus ) in aquatic Acute Category 1.
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