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EC number: 203-581-0 | CAS number: 108-42-9
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The effective concentration (EC50) value of 3-chloroaniline in aquatic invertebrate (Daphnia magna) in a 48 hr study on the basis of intoxication effect was found to be 0.35 mg/L.Thus considering the CLP Criteria for aquatic classification of the substance , it is concluded that 3-chloroaniline exhibits short term toxicity to aquatic invertebrate (Daphnia magna) in aquatic Acute Category 1.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.35 mg/L
Additional information
No. of studies were reviewed for Short-term toxicity to aquatic invertebrates from reliable sources having Klimisch rating 2 and 4.
The summary of the results are presented below
Sr.No |
Endpoint |
Effect values |
Basis for effects |
Duration |
Species |
Sources |
1 |
EC50 |
0.35 mg/L |
Intoxication |
48 hrs. |
Daphnia magna (Water Flea) |
Experimental data from Water Research for CAS : 108-42-9 |
2 |
EC0 |
0.4 mg/L |
Behaviour |
24 hrs. |
Daphnia magna (Water Flea) |
Experimental data from Forschungsbericht for CAS : 108-42-9 |
3 |
LC50 |
0.1 mg/L |
Mortality |
48 hrs. |
Daphnia magna (Water Flea) |
Experimental data for CAS : 108-42-9 |
4 |
EC50 |
0.44 mg/L |
Intoxication |
48 hrs. |
Daphnia longispina |
Experimental data from Environmental Toxicology and Chemistry for RA CAS : 95-76-1
|
Based on the studies summarized in the above table for the target substance 3-chloroaniline and the read across substance 3,4-dichloroaniline,the endpoint value was found to vary between effective concentration (EC50) = 0.35 mg/L to 0.44 mg/L,lethal concentration (LC50) = 0.1 mg/L and EC0 = 0.4 mg/L in a 24 hr. to 48 hrs. study on the basis of intoxication,behaviour and mortality effect. Based on the EC50,EC0 and LC50 values and considering the CLP Criteria for aquatic classification of the substance , it is concluded that 3-chloroaniline exhibits short term toxicity to aquatic invertebrate (Daphnia magna and Daphnia longispina) in aquatic Acute Category 1.
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