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Use of read-across to fill data gaps for the subject of Registration,Neononanoic acid glycidyl ester (2,3 -epoxypropyl neonoanoate) CAS No. 144548 -01-6, from 2,3 -epoxypropyl neodecanoate (EC No. 247-979-2/CAS No. 26761-45-5/REACH Registration: 01-2119431597-33-0000) is justified in the attachment.

The structural analog test substance, 2,3-epoxypropyl neodecanoate had acute (96 hr) rainbow trout (O.E.C.D. 203) and Daphnia (48 hr/O.E.C.D. 202) EC/LC50 values of approximately 5 mg/L. Green algae was the most sensitive aquatic species to the test substance with a mean EC50 (72 hr) value of 1.4 mg/L. Therefore, this value is most appropriate for establishing aquatic PNECs for the structural analog and Neononanoic acid glycidyl ester. The EC50 value for 2,3-epoxypropyl neodecanoate for activated sludge (O.E.C.D. test guideline 209) was > 500 mg/L.