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EC number: 940-029-4
CAS number: 1474044-86-4
The structural analog test substance, 2,3-epoxypropyl
neodecanoate was accessed for the potential to induce gene-mutation in
the in vivo MutaMouse test system up to an oral dose level of 1000 mg/kg
by an O.E.C.D. test guideline 488 study. The test substance is a
gene-mutagen in vivo in the MutaMouse. Treatment wiht the test substance
induced a statisticall significant, dose-related increase of the mutant
frequency in the liver, kidney and bone marrow of the MutaMouse. No
increase of the mutant frequency was observed in the developing and
mature sperm. Therefore, the test substance, 2,3-epoxypropyl
neodecanoate is a CLP Category 2 Mutagen, H341, "Suspected of causing
genetic defects". This Classification and Labeling is considered to be
appropriate for the subject of Registration, Neononanoic acid glycidyl
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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