Registration Dossier
Registration Dossier
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EC number: 470-740-0 | CAS number: 29721-79-7
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 04 Dec 2006
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: done under GLP and OECD method
Data source
Reference
- Reference Type:
- other: Unnamed report
- Title:
- Unnamed
- Year:
- 2 007
- Report date:
- 2007
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Version / remarks:
- Directive 92/69/EEC
- GLP compliance:
- yes
- Remarks:
- Directives 2004/9/EC and 2004/10/EC
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
- Test material form:
- liquid
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficientopen allclose all
- Type:
- Pow
- Partition coefficient:
- 5.922
- Temp.:
- 30 °C
- Remarks on result:
- other: ± 0.1
- Remarks:
- pH not specified
- Type:
- log Pow
- Partition coefficient:
- 0.772
- Temp.:
- 30 °C
- Remarks on result:
- other: pH not specified
- Details on results:
- Mean log10 Pow: 0.772
Any other information on results incl. tables
Preliminary estimates |
|
The preliminary test (saturation with each of the phases) leads to a value of log POw , of 18.8 with the following approximate solubility concentrations: |
|
-- 223 g/l in the octanol; 11.9g/l in the water (indications provided by the principal). |
|
Applicant's summary and conclusion
- Conclusions:
- The partition coefficient has been determined to be 5.92, log 10 Pow 0.772
- Executive summary:
Substances having a log10 Pow greater than 3 are regarded as having the potential to bioaccumulate in the enviroment.
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