Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 480-340-8 | CAS number: -
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.1 mg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 1 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.01 mg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
- PNEC marine water (intermittent releases):
- 1 mg/L
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 1 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.46 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.046 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.049 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
No data are available for the assessment of the acute toxicity potential of the substance to fish. For this reason data on the dissociation substances were used for the the evaluation of short-term toxicity to fish. For algae, daphnia and microorganisms there are available data on the substance toxicity potential. The results of the studies for each organism are presented below.
Short-term toxicity to fish
Three studies from literature are used for the assessment of the toxicity of perchlorate to the fish after 96 hours of exposure.
- Zebrafish Danio rerio lavrae, static-renewal, ASTM E729 -90: LC50 (96 h) = 1365 mg/l (measured).
- Juvenille zebrafish Danio rerio, static-renewal, ASTM E792 -96: LC50 (96 h) = 2532 mg/l (measured).
- Rainbow trout fry and juvenille bluegill sunfish, flow-through, EPA OPPTS 850.1075, ASTM E729 -96, 2000: for rainbow trout: EC50 (96 h) = 2010 mg/l (mean measured); for bluegill sunfish: EC50 (96 h) = 1470 mg/l (mean measured).
Two studies from literature are used for the assessment of the toxicity of triethanolamine to fish.
Fathead minnows, flow-through: LC50 (96 h) = 11.8 g/l (measured), EC50 (96 h) = 11.8 g/l (measured).
Goldfish, APHA (1971): LC50 (24 h) > 5000 mg/l (measured).
For the chemical safety assessment an EC50 of 1470 mg/l is used based on a study on perchlorate. This value is one of the lowest values obtained in all the studies available (worst case senario). A lowest value determined in another study was 1365 mg/l (LD50) but even if this value is lower, it is not used for the chemical safety assessment since an EC50 instead of LC50 is used as it takes in consideration severe effects and not only mortality.
Short-term toxicity to aquatic invertebrates
Daphnia magna, limit static test, OECD 202, EU C.2: EC50 > 100 mg/l (nominal).
Toxicity to aquatic algae and cyanobacteria
Desmodesmus subspicatus, OECD 201, EU C.3: ErC50 (72 h) > 460 mg/l (nominal), NOEC (growth rate) = 10 mg/l (nominal),EbC50 (72 h) = 380 mg/l (nominal) and EyC50 (72 h) = 230 mg/l (nominal).
Toxicity to microorganisms
OECD guideline 209, EU C.11: EC50 (3 h) > 1000 mg/l (nominal), NOEC (3 h)≈ 10 mg/l (nominal)
Conclusion on classification
Based on the available studies the following results were obtained for daphnia and algae. No data are available for the assessment of the acute toxicity potential of the substance to fish. For this reason data on the dissociation substances were used for the evaluation of short-term toxicity to fish and the EC50 value chocen amongst others was the one obtained for perchlorate.
For the evaluation of the classification of the substance the following effect concentrations are taken into consideration:
- for daphnia: EC50 (48h) > 100 mg/l (nominal) and
- for algae: ErC50 (72h, growth rate) > 460 mg/l (nominal) and NOEC (72h, growth rate) = 10 mg/l (nominal).
- for fish (juvenille bluegill sunfish): EC50 (96h) = 1470 mg/l (measured)
The substance is readily biodegradable and the EC50 for the three trophic levels is higher than the threshold for classification.
According to the CLP Regulation (EC) No. 1272/2008, a classification as harmful/toxic for aquatic life is not proposed for the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
