Registration Dossier
Registration Dossier
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EC number: 690-796-1 | CAS number: 420-16-6
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Effect on fertility: via oral route
- Endpoint conclusion:
- no study available
Effect on fertility: via inhalation route
- Endpoint conclusion:
- no study available
Effect on fertility: via dermal route
- Endpoint conclusion:
- no study available
Additional information
Dangerous Substance Directive (67/548/EEC)
The substance does not need to be classified and labelled for reproductive toxicity under Directive 67/548/EEC, as amended for the 31st time in Directive 2009/2/EC.
Classification, Labelling, and Packaging Regulation (EC) No 1272/2008
The substance does not need to be classified and labelled for reproductive toxicity under Regulation (EC) No 1272/2008, as amended for the sixth time in Regulation EC No 605/2014.
Short description of key information:
No experimental study is available. The test substance is intended for use in an industrial setting only, and thus oral uptake is not an anticipated route of exposure. Upon hydrolysis of the test substance, boron trifluoride and acetonitrile are formed among other dissociation products. The test substance itself and its direct hydrolysis products are highly corrosive and would lead to severe parental toxicity well before internal doses of the hydrolysis products are reached that could potentially cause effects on fertility or development. This would also result in unwarranted distress for the animals. Therefore, any reproductive study with the test substance is scientifically unjustified. Due to the corrosive properties of the substance, suitable risk management measures for dermal and inhalative exposure need to be taken (gloves, respiratory protection). Relevant human exposure via oral, dermal and inhalative uptake can be excluded, which justifies waiving of developmental toxicity and teratogenicity testing according to annex XI, section 3 of Regulation (EC) 1907/2006 (REACH).
Justification for classification or non-classification
Dangerous Substance Directive (67/548/EEC)
The substance does not need to be classified and labelled for reproductive toxicity under Directive 67/548/EEC, as amended for the 31st time in Directive 2009/2/EC.
Classification, Labelling, and Packaging Regulation (EC) No 1272/2008
The substance does not need to be classified and labelled for reproductive toxicity under Regulation (EC) No 1272/2008, as amended for the sixth time in Regulation EC No 605/2014.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
