Registration Dossier

Diss Factsheets

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008-12-10 to 2008-12-11
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient)
Version / remarks:
EC-No. 440/2008
Deviations:
no
Principles of method if other than guideline:
NA
GLP compliance:
yes
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
< 0.3
Temp.:
20 °C
pH:
6
Details on results:
NA
Conclusions:
A log Pow of 0.127 was measured. This value lies outside the range of the recommended reference items. Therefore, the log Pow of the test item sodium cyanate is stated as < 0.3.
Executive summary:

A log Pow of 0.127 was measured (HPLC-Method). This value lies outside the range of the recommended reference items. Therefore, the log Pow of the test item sodium cyanate is stated as < 0.3.

Description of key information

A log Pow of 0.127 was measured (HPLC-Method). This value lies outside the range of the recommended reference items. Therefore, the log Pow of the test item sodium cyanate is stated as < 0.3. 

Key value for chemical safety assessment

Log Kow (Log Pow):
0.3
at the temperature of:
20 °C

Additional information