Registration Dossier
Registration Dossier
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EC number: 229-633-2 | CAS number: 6635-20-7
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Classification of 5-nitrovanillinfor effects in the environment
In determining the classification appropriate to 5-nitrovanillin, it is necessary to consider all available evidence concerning its persistence, potential to accumulate and predicted or observed environmental fate and behaviour that may present a long-term and/or delayed danger to the structure and/or functioning of aquatic ecosystems. These points are considered below.
Persistence
Reliable studies are available to demonstrate that 5-nitrovanillin is non persistent in the aquatic environment as it is considered to have rapid biodegradation in the water. However, it is persistent in the soil and sediment compartment. Thus, it can be inferred that 5-nitrovanillin is persistent in character.
5-nitrovanillin is therefore classified as a persistent (P) chemical.
Potential to accumulate
The measured log Kow values for 5-nitrovanillin is less than 4 (Log Kow = 0.301). The potential for 5-nitrovanillin to bioaccumulate in the tissues of organisms; that inhabit aquatic or terrestrial matrices is negligible as the BCF factor for the substance is less than 1000.
The calculated BCF of 5-nitrovanillin is 4.2 dimensionless and below the threshold of 2000.
5-nitrovanillindoes not satisfy the criterion for classification as bioaccumulative (B).
The toxicity values of fish, invertebrates and algae are LC50 =114.9535mg/L, LC50 =131.7071mg/L are EC50 =102.496mg/L, respectively. Thus, based upon these values, it is considered that 5-nitrovanillin shall not exhibit aquatic toxicity within the dose levels mentioned in the three aquatic trophic levels
So, 5-nitrovanillindoes not satisfy the environmental effects criterion for classification as aquatic toxic chemical (T).
Thus it can be inferred that 5-nitrovanillin is Persistent (P) but not a bio-accumulative and toxic chemical
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