Registration Dossier
Registration Dossier
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EC number: 247-988-1 | CAS number: 26762-93-6
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
OECD Guideline 111, GLP, key study, validity 2:
Half-life (pH 1.2; 37 °C) = 28.2 hours
Key value for chemical safety assessment
Additional information
One valid key study is available to determine the rate of hydrolysis of the test substance in different buffers and at different temperatures, according to the OECD Guideline 111 with GLP statement (Gancet, 2013).
A preliminary test showed that the item was stable at pH 4, 7 and 9 at 50°C during 5 days. At pH 1.2, strong hydrolysis can be observed in the same conditions. The definitive test was conducted at pH 1.2 and at 15, 37 and 50°C.
The half-life for the test substance at pH 1.2 and 37 °C is equivalent to 28.2 hours.
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