Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

3-Cyanopyridine is not irritating to skin, but causes severe damage to eyes.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

3-Cyanopyridine was found to be non-irritating to the skin of rabbits after 3 or 60 minutes, and 4 hours. However, application of 0.1 ml into the eyes of rabbits resulted in severe damage which persisted throughout 21 days. There is no data available for respiratory irritation.


Effects on eye irritation: highly irritating

Justification for classification or non-classification

3 -Cyanopyridine is not classified for irritation to skin or the respiratory tract. It is classified for eye irritation as a Category 1 substance, causing severe damage to the eye, according to Regulation (EC) No. 1272/2008.