Registration Dossier
Registration Dossier
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EC number: 202-863-0 | CAS number: 100-54-9
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study by the Japanese CHIRP NITE
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 1 994
- Report date:
- 1994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- Principles of method if other than guideline:
- MITI according to Japanese standard protocol
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Nicotinonitrile
- EC Number:
- 202-863-0
- EC Name:
- Nicotinonitrile
- Cas Number:
- 100-54-9
- Molecular formula:
- C6H4N2
- IUPAC Name:
- pyridine-3-carbonitrile
- Reference substance name:
- Pyridine-3-carbonitrile
- IUPAC Name:
- Pyridine-3-carbonitrile
Constituent 1
Constituent 2
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- 30 mg/l activated sludge was used.
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
Reference substance
- Reference substance:
- not specified
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 1
- Sampling time:
- 28 d
- Parameter:
- % degradation (inorg. C analysis)
- Value:
- 0
- Sampling time:
- 28 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 1
- Sampling time:
- 28 d
- Details on results:
- Not readily biodegradable
BOD5 / COD results
- Results with reference substance:
- assume acceptable
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- according to Japanese NITE requirements
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- 3-Cyanopyridine was not readily biodegradable in a ready biodegradability test using the MITI (OECD 301C) protocol.
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